Proteoglycan Replacement Therapy
Proteoglycans are essential regulators of metabolic pathways in humans. Multiple clinical papers, published in leading peer-reviewed journals, document that even a slight increase in the metabolic balance of proteoglycans can have a disproportionately large impact on their effectiveness.
Understanding Proteoglycan Replacement Therapy for Hair Growth
For over three decades, significant research has zeroed in on the hair follicle, elucidating its unique life cycle, functionality, and cyclical behaviour. One major discovery during this period is the pivotal role that proteoglycans – a specific type of activation protein – play in fostering healthy hair growth.
Proteoglycans are integral to the hair follicle’s ability to maintain a balanced dialogue between its various compartments and to modulate growth factors effectively. This finely tuned interplay is vital to the normal functioning of the Hair Growth Cycle.
The Hair Growth Cycle is a structured sequence comprising three phases:
- Anagen (growth) phase.
- Catagen (transition) phase.
- Telogen (resting) phase.
At the culmination of the Telogen phase, hair is shed, ushering in a new Anagen phase, and thus, the cycle repeats itself.
A myriad of factors can disrupt this cycle, however, culminating in hair shedding, and in some cases, stunted or even no re-growth. One of the underlying causes for such disruptions is termed ‘Proteoglycan Follicular Atrophy’. This condition arises due to a decrease in proteoglycan levels within the hair follicle, commonly associated with age-related or genetic hair loss (Androgenetic Alopecia), post-pregnancy (Postpartum Effluvium), and stress-induced hair loss (Telogen Effluvium).
Proteoglycan Replacement Therapy (PRT) addresses this decline. PRT involves the oral administration of bioavailable proteoglycans, aiming to bolster the concentration of specific hair follicle proteoglycans. This therapeutic intervention seeks to normalise the Hair Growth Cycle, thereby promoting the genesis of new, healthy hair growth. Its targeted action against Proteoglycan Follicular Atrophy makes it an effective treatment for both male and female hair loss patterns. As such, Proteoglycan Replacement Therapy is gaining traction globally, with many adopting it as a standalone treatment or in conjunction with other therapies.
For individuals grappling with hair loss or hair growth disorders, Proteoglycan Replacement Therapy emerges as a scientifically backed, primary treatment solution. Its focus on addressing the root cause – Proteoglycan Follicular Atrophy – ensures a holistic approach to restoring and maintaining the natural Hair Growth Cycle.
Effect of Proteoglycan Replacement Therapy